Pharmaceutics Notes
Chapter 1
History of the profession of Pharmacy in India in relationto Pharmacy education, industry, pharmacy practice,and various professional associations.
Pharmacy as a career
Pharmacopoeia: Introduction to IP, BP, USP, NF andExtra Pharmacopoeia. Salient features of IndianPharmacopoeia
Chapter 2
Packaging materials: Types, selection criteria,advantages and disadvantages of glass, plastic, metal,rubber as packaging materials
Chapter 3
Pharmaceutical aids: Organoleptic (Colouring, flavouring,and sweetening) agents
Preservatives: Definition, types with examples and uses
Chapter 4
Unit operations: Definition, objectives/applications,principles, construction, and workings of:
Size reduction: hammer mill and ball mill
Size separation: Classification of powders according to IP,Cyclone separator, Sieves and standards of sieves
Mixing: Double cone blender, Turbine mixer, Triple rollermill and Silverson mixer homogenizer
Filtration: Theory of filtration, membrane filter and sinteredglass filter
Drying: working of fluidized bed dryer and process offreeze drying
Extraction: Definition, Classification, method, andapplications
Chapter 5
Tablets – coated and uncoated, various modified tablets(sustained release, extended-release, fast dissolving, multi-layered, etc.)
Capsules - hard and soft gelatine capsules
Liquid oral preparations - solution, syrup, elixir, emulsion,suspension, dry powder for reconstitution
Topical preparations - ointments, creams, pastes, gels,liniments and lotions, suppositories, and pessaries
Nasal preparations, Ear preparations
Powders and granules - Insufflations, dusting powders,effervescent powders, and effervescent granules
Sterile formulations – Injectables, eye drops and eyeointments
Immunological products: Sera, vaccines, toxoids, andtheir manufacturing methods.
Chapter 6
Basic structure, layout, sections, and activities ofpharmaceutical manufacturing plantsQuality control and quality assurance: Definition andconcepts of quality control and quality assurance, currentgood manufacturing practice (cGMP), Introduction to theconcept of calibration and validation
Chapter 7
Novel drug delivery systems: Introduction, Classificationwith examples, advantages, and challenges